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CD38 Mouse anti-Human, Alexa Fluor® 700, Clone: HIT2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 56-0389-41

Additional Details : Weight : 0.23750kg

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Product Code. 15500357

  • 1280.00 SEK / 25 tests


Estimated Shipment date
from Supplier 25-04-2019
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Description

Description

CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, maligt lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter’s Syndrome.
Specifications

Specifications

CD38
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P28907
T10, ADP-ribosyl cyclase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase, CD38 antigen p45, NAD+ nucleosidase, cADPr hydrolase 1, cyclic ADP-ribose hydrolase 2
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
HIT2
Alexa Fluor® 700
CD38
Liquid
CD38
IgG1, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
952
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