missing translation for 'onlineSavingsMsg'
Learn More

CD4 Rat anti-Mouse, Biotin, Clone: RM4-5, eBioscience™

Rat Monoclonal Antibody

532.00 SEK - 3500.00 SEK

Specifications

Antigen CD4
Clone RM4-5
Target Species Mouse
Conjugate Biotin
Isotype IgG2a, kappa
View More Specs

Products 4
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15289409
View Documents
Affymetrix eBioscience
13-0042-81
50 μg
532.00 SEK
50µg
View alternative products
Save Up to 
»
Estimated Shipment: 09-09-2021
Please to purchase this item. Need a web account? Register with us today!
15299409
View Documents
Affymetrix eBioscience
13-0042-82
100 μg
886.00 SEK
100µg
View alternative products
Save Up to 
»
Estimated Shipment: 13-08-2021
Please to purchase this item. Need a web account? Register with us today!
15209419
View Documents
Affymetrix eBioscience
13-0042-85
500 μg
2010.00 SEK
500µg
View alternative products
Save Up to 
»
Estimated Shipment: 13-08-2021
Please to purchase this item. Need a web account? Register with us today!
15219419
View Documents
Affymetrix eBioscience
13-0042-86
1 mg
3500.00 SEK
1mg
View alternative products
Save Up to 
»
Estimated Shipment: 13-08-2021
Please to purchase this item. Need a web account? Register with us today!
Description

Description

Description: The RM4-5 monoclonal antibody reacts with the mouse CD4 molecule, a 55 kDa cell surface receptor expressed by a majority of thymocytes, subpopulation of mature T cells and dendritic cells. CD4 binds to MHC class II on the surface of antigen presenting cells and plays an important role both in T cell development and in optimal functioning of mature T cells. In T cells, CD4 associates with protein tyrosine kinase p56lck through its cytoplasmic tail. Binding of RM4-5 is blocked by GK1.5. Applications Reported: The RM4-5 antibody has been reported for use in flow cytometric analysis. Applications Tested: The RM4-5 antibody has been tested by flow cytometric analysis of mouse thymocytes and splenocytes. This can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered.

The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].
Specifications

Specifications

CD4
Mouse
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
RM4-5
Biotin
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO
SDS
Product Certifications

For Research Use Only.