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CD4 Rat anti-Mouse, Functional Grade, Clone: GK1.5, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-0041-95

Additional Details : Weight : 0.09500kg

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Product Code. 15507776

  • 21020.00 SEK / 10mg


Estimated Shipment date
from Supplier 01-08-2019
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Description

Description

Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].
Specifications

Specifications

CD4
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
P06332
CD4 antigen p55, CD4 receptor, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry, Functional Assay, Neutralization
GK1.5
Functional Grade
Cd4
Liquid
Cd4
IgG2b, kappa
10 mg
4° C
Primary
12504
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