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CD40 Monoclonal Antibody (5C3), Alexa Fluor™ 700, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

1654.00 SEK - 3935.00 SEK

Specifications

Antigen CD40
Clone 5C3
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Product Code Brand Quantity Price Quantity & Availability  
16606434
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Affymetrix eBioscience
56-0409-42
100 Tests
3935.00 SEK
100 tests
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16696424
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Affymetrix eBioscience
56-0409-41
25 Tests This item is currently unavailable or has been discontinued.
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Description

Description

Description: The 5C3 monoclonal antibody reacts with human CD40, a 45-50 kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development and maturation by inducing Ig isotype-switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation. 5C3 is reported to be used for activation of B cells in in vitro functional assays. Applications Reported: This 5C3 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 5C3 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

CD40 Monoclonal antibody specifically detects CD40 in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD40
5 μL/Test
Monoclonal
Liquid
RUO
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
958
IgG1 κ
Affinity chromatography
CD40
5C3
Flow Cytometry
Alexa Fluor 700
Mouse
Human
P25942
CD40
Primary
Antibody
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