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CD41/Integrin alpha 2b Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 18308-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16878384

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.
Specifications

Specifications

CD41/Integrin alpha 2b
0.17 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P08514, Q9QUM0
CD41, CD41B, GP2B, GPalpha IIb, GPIIb, GTA, HPA3, Integrin alpha IIb, ITGA2B, ITGAB
Rabbit
IgG
20 μL
-20°C
Primary
16399, 3674, 685269
Immunohistochemistry (Paraffin)
Unconjugated
ITGA2B
Liquid
Itga2b
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Rat, Human, Mouse
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