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CD41a, PE, clone: eBioMWReg30 (MWReg30), eBioscience™

Rat Monoclonal Antibody

860.00 SEK - 2590.00 SEK

Specifications

Antigen CD41a
Clone eBioMWReg30 (MWReg30)
Target Species Murine
Conjugate PE
Isotype IgG1, kappa, kappa
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15228529 Affymetrix eBioscience
12-0411-81
50μg 860.00 SEK
50µg
EU Stock 1
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15238529 Affymetrix eBioscience
12-0411-82
100μg 1726.00 SEK
100µg
EU Stock 5
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15248529 Affymetrix eBioscience
12-0411-83
200μg 2590.00 SEK
200µg
Estimated Shipment date
from Supplier 29-01-2019
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Description

Description

Description: The eBioMWReg30 monoclonal antibody reacts with mouse CD41 (fibrinogen receptor, gpIIb, integrin alpha IIb). While initially thought to be expressed exclusively on the surface of platelets and megakaryocytes, it has been demonstrated that CD41 is also expressed on hematopoietic progenitors in the embryo, fetus and adult. CD41 associates with CD61 (gpIIIa, integrin beta III) to form a receptor which plays a major role in platelet function, including binding of several adhesion molecules such as fibrinogen, fibronectin and vitronectin.Recently, the SLAM-family markers, CD48 and CD150 have been used to reliably identify hematopoietic stem cells (HSC). Specifically, it was found that CD150+CD48- bone marrow cells were highly efficient in their ability to confer long-term multi-lineage reconstitution in irradiated mice. Furthermore, the efficiency of reconstitution was enhanced when HSCs were further enriched through the exclusion of CD41+ cells. Thus, the use of CD150+CD48-CD41- as an expression profile efficiently identifies hematopoietic stem cells.Applications Reported: This eBioMWReg30 (MWReg30) antibody has been reported for use in flow cytometric analysis.Applications Tested: This eBioMWReg30 (MWReg30) antibody has been tested by flow cytometric analysis of mouse platelets. This can be used at less than or equal to 0.125 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD41a
Murine
IgG1, kappa, kappa
Monoclonal
Liquid
Antibody
Store at 2-8°C. Do not freeze. Light-sensitive material.
eBioMWReg30 (MWReg30)
PE
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.