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CD42d Monoclonal Antibody (1C2), eBioscience™, Invitrogen™

Armenian Hamster Monoclonal Antibody

856.00 SEK - 2185.00 SEK

Specifications

Antigen CD42d
Clone 1C2
Concentration 0.5 mg/mL
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Classification Monoclonal
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15276947
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Affymetrix eBioscience
14-0421-82
100 μg
2185.00 SEK
100µg
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15266947
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Affymetrix eBioscience
14-0421-80
25 μg This item is currently unavailable or has been discontinued.
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Description

Description

Description: The monoclonal antibody 1C2 recognizes mouse and rat CD42d, a single transmembrane protein also known as platelet glycoprotein V (GPV). CD42d interacts with CD42a, CD42b and CD42c to form the receptor for von willebrand factor and thrombin. This functional complex plays a role in platelet adhesion. Expression of CD42d (unlike other markers such as CD41) is restricted to resting platelets and megakaryocytes and therefore is a good marker for development of megakaryocytes. Applications Reported: This 1C2 antibody has been reported for use in flow cytometric analysis, immunoprecipitation, and immunohistology staining of frozen tissue sections. Applications Tested: This 1C2 antibody has been tested by flow cytometric analysis of mouse platelets. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

Natural killer (NK) cells in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. NK cells are important effectors of innate immunity where they release cytokines, which in turn up-regulate other immunological functions. Monoclonal antibodies have been used to identify different surface antigens present on NK cells. These surface antigens have not only been used to identify NK cells, but also their functionally distinct subsets. The Cluster of Differentiation (CD) nomenclature was established to standardize the naming of NK cells.
Specifications

Specifications

CD42d
0.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
CD42d; Glycoprotein 5; glycoprotein 5 (platelet); glycoprotein 5, platelet; glycoprotein V (platelet); glycoprotein V platelet; GP5; GPV; Platelet glycoprotein 5; platelet glycoprotein V; Platelete glycoprotein 5; Platelets GP V; PLGPV
Gp5
Primary
4° C
Gp5
1C2
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Unconjugated
Armenian Hamster
Mouse, Rat
O08742, O08770
14729, 25259
IgG
Affinity chromatography
Antibody
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