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CD43 Monoclonal Antibody (4-29-5-10-21), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
1128.00 SEK - 2875.00 SEK
Specifications
| Antigen | CD43 |
|---|---|
| Clone | 4-29-5-10-21 |
| Concentration | 5 μL/Test |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15519126
|
Affymetrix eBioscience
46-0438-41 |
25 Tests |
1128.00 SEK
25 tests |
Estimated Shipment: 28-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
15529126
|
Affymetrix eBioscience
46-0438-42 |
100 Tests |
2875.00 SEK
100 tests |
Estimated Shipment: 28-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
CD43 (leukosialin, sialophorin) is a transmembrane mucin-like protein with high negative charge, expressed on the surface of most hematopoietic cells. CD43 contributes to a repulsive barrier that interferes with cellular adhesion, however, in certain cases also promotes leukocyte aggregation. By interaction with actin-binding proteins ezrin and moesin CD43 plays a regulatory role in remodeling T-cell morphology and regulates cell-cell interactions during lymphocyte traffic. CD43 signaling both enhances LFA-1 adhesiveness and counteracts LFA-1 induction via other receptors. Expression of CD43 causes induction of functionally active tumour suppressor p53 protein, but in case of p53 and ARF defficiency CD43 promotes tumour proliferation and viability. It appears to be an important modulator of leukocyte functions.
CD43 Monoclonal antibody specifically detects CD43 in Human, Non-human Primate samples. It is validated for Flow Cytometry.Specifications
| CD43 | |
| 5 μL/Test | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
| 3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen | |
| SPN | |
| Primary | |
| 4° C, store in dark, DO NOT FREEZE! | |
| SPN |
| 4-29-5-10-21 | |
| Flow Cytometry | |
| PerCP-eFluor 710 | |
| Mouse | |
| Human, Non-human Primate | |
| P16150 | |
| 6693 | |
| IgG1 κ | |
| Affinity chromatography | |
| Antibody |
For Research Use Only.