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CD45, TRI-COLOR, clone: HI30, Invitrogen™

Mouse Monoclonal Antibody

3565.00 SEK - 14620.00 SEK

Specifications

Antigen CD45
Clone HI30
Applications Flow Cytometry
Classification Monoclonal
Conjugate TRI-COLOR
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
10058202
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Invitrogen
MHCD4506
0.5 mL
3565.00 SEK
Each
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Estimated Shipment: 14-02-2023
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10119852
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Invitrogen
MHCD45065
2.5 mL
14620.00 SEK
Each
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»
Estimated Shipment: 20-02-2023
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Description

Description

CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells.

The TRI-COLOR™ conjugate is a tandem R-phycoerythrin (PE)-Cy5™ conjugate that permits simultaneous multicolor labeling and detection of multiple targets with excitation by a single excitation source-the 488 nm line of the argon-ion laser.
Specifications

Specifications

CD45
Flow Cytometry
TRI-COLOR
Mouse
Human
P08575
5788
CD45 antigen
Primary
Store at 2 - 8 °C.
PTPRC
HI30
Monoclonal
Liquid
ASR/IVD, ASR
PBS with BSA, sucrose and 0.1% sodium azide
B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, CD45 antigen, T200 glycoprotein, T200 leukocyte common antigen, protein tyrosine phosphatase, receptor type, c polypeptide, receptor-type tyrosine-protein phosphatase C
PTPRC
IgG1
Purified
Antibody
SDS
Product Certifications