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CD45RB, Alexa Fluor 488, clone: PD7/26, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-9458-82

Additional Details : Weight : 0.09500kg

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Product Code. 15520277

  • 2760.00 SEK / 100µg


Estimated Shipment date
from Supplier 25-07-2018
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Description

Description

Description: The monoclonal antibody PD7/26 recognizes CD45RB, which is an isoform of the Leukocyte Common Antigen (LCA) also known as CD45. CD45RB is a protein tyrosine phosphatase receptor that is present on most hematopoietic cells and absent on non-hematopoietic cells. Expression of CD45RB is more restricted than CD45 and can only be found on T cell subsets, B, NK, and myeloid cells. Regulatory T cells (Tregs) have been show to express low levels of CD45RB, which may correlate with increased migration to sites of infection. In contrast, high CD45RB expression results in IL-2 and IFN gamma production instead of IL-4 in vitro.Applications Reported: This PD7/26 antibody has been reported for use in flow cytometric analysis, immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, microscopy, and immunocytochemistry.Applications Tested: This PD7/26 antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded tissue using low pH antigen retrieval and can be used at less than or equal to 10 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD45RB
Monoclonal
0.5mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P08575
B220, CD45, CD45R, GP180, LCA, LY5, T200
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow CytometryþImmunocytochemistryþImmunohistochemistryþMicroscopy
PD7/26
Alexa Fluor 488
PTPRC
Conjugated
PTPRC
IgG1, kappa
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
5788
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