CD49f (Integrin alpha 6), Biotin, clone: eBioGoH3 (GoH3), eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 13-0495-82
Additional Details : Weight : 0.25000kg
DescriptionDescription: The eBioGoH3 monoclonal antibody reacts with mouse and human CD49f, also known as integrin alpha 6, very late activation antigen 6 (VLA-6 alpha chain), and platelet gpIc. CD49f is a 120 kD transmembrane protein. CD49f associates with CD29, the integrin beta 1 chain, to form the VLA-6 complex; CD49f also associates with CD104, the integrin beta 4 chain, to form the alpha 6 beta 4 complex. CD49f is expressed primarily on T cells, monocytes, platelets, epithelial and endothelial cells. CD49f expression has also been found on germinal center B cells. The eBioGoH3 antibody is cross-reactive to integrin alpha 6 on human, mouse and bovine cells. This antibody has also been reported to have functional activity in blocking the binding of integrin alpha 6 to laminin.Applications Reported: This eBioGoH3 (GoH3) antibody has been reported for use in flow cytometric analysis, and immunohistology staining of frozen tissue sections.Applications Tested: This eBioGoH3 (GoH3) antibody has been tested by flow cytometric analysis of human peripheral blood cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
|CD49f (Integrin alpha 6)|
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|CD49f, DKFZp686J01244, FLJ18737, ITGA6B, VLA-6|
|Flow Cytometry, Immunohistochemistry (Frozen)|
|IgG2a, kappa, kappa|
|Store at 2-8°C. Do not freeze.|
For Research Use Only.