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CD5 Mouse anti-Human, APC, Clone: UCHT2, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-0059-41

Additional Details : Weight : 0.01000kg

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Product Code. 16606304

  • 1292.00 SEK / 25 tests
Estimated Shipment: 29-08-2022
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Description

Description

Description: The UCHT2 monoclonal antibody reacts with human CD5, a 67 kDa protein expressed by a majority of thymocytes and mature T cells and a subset of B cells. Signaling through the CD5 molecule activates T cells and binding of CD5 to its ligand on B cells, CD72, and plays an important role in T-B interaction and proliferation. The monoclonal antibody UCHT2 recognizes primate CD5. Applications Reported: This UCHT2 antibody has been reported for use in flow cytometric analysis. Applications Tested: This UCHT2 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.

CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter′s Syndrome.
Specifications

Specifications

CD5
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
P06127
Cd5
Affinity chromatography
RUO
921
4°C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
UCHT2
APC
Cd5
BOS_24667; CD antigen CD5; Cd5; CD5 antigen; CD5 antigen (p56-62); CD5 antigen p56-62; CD5 molecule; CD74 antigen, invariant polypeptide of major; fCD5; LEU1; Ly-1; Ly-12; Ly-A; Lymphocyte antigen 1; Lymphocyte antigen CD5; Lymphocyte antigen T1/Leu-1; Lyt-1; Pan T cell; T1; T-cell surface glycoprotein CD5
Mouse
25 Tests
Primary
Human
Antibody
IgG1 κ
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