CD51/CD61 (Integrin alpha v beta 3), Biotin, clone: 23C6, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 13-0519-80
Additional Details : Weight : 0.25000kg
DescriptionDescription: The 23C6 monoclonal antibody reacts with the human CD51/CD61 dimer, also known as the integrin alphav/beta3. CD51, an ∽120kDa surface molecule can also non-covalently associate with other beta subunits of the integrin family including beta1 (CD29), beta5 and beta6 to form receptors for extracellular matrix components. Heterodimers of CD51/CD61 are expressed by melanoma cells, endothelial cells and osteoclasts and at very low levels by platelets. The CD51/CD61 complex mediates adhesion to fibrinogen, fibronectin, vitronectin and thrombospondin.Applications Reported: This 23C6 antibody has been reported for use in flow cytometric analysis.Applications Tested: This 23C6 antibody has been tested by flow cytometric analysis of peripheral blood cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
|CD51/CD61 (Integrin alpha v beta 3)|
|PBS with 0.09% sodium azide; pH 7.2|
|ITGAV, ITGB3, CD51, MSK8, VNRA, VTNR, integrin alpha-V, integrin alphaVbeta3, antigen CD51, vitronectin receptor subunit alpha, CD61, GP3A, GPIIIa|
|IgG1, kappa, kappa|
|Store at 2-8°C. Do not freeze.|
For Research Use Only.