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CD51 (Integrin alpha V), clone: RMV-7, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0512-85

Additional Details : Weight : 0.01000kg

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Product Code. 15247017

  • 2005.00 SEK / 500µg


Estimated Shipment date
from Supplier 03-06-2019
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Description

Description

ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8, ′ITGB1′, ′ITGB3′, ′ITGB5′, ′ITGB6′, and ′ITGB8′), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
Specifications

Specifications

CD51 (Integrin alpha V)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P43406
Vitronectin Receptor alpha chain, VNR
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry, Functional Assay, Immunoprecipitation, Neutralization
RMV-7
Unconjugated
Itgav
Liquid
Itgav
IgG1, kappa
500 μg
4° C
Primary
16410
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