missing translation for 'onlineSavingsMsg'
Learn More

CD51 (Integrin alpha V), clone: RMV-7, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0512-85

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15247017

  • 1964.00 SEK / 500µg


Estimated Shipment date
from Supplier 21-11-2018
Add to basket

Description

Description

Description: The RMV-7 monoclonal antibody reacts with the mouse CD51 molecule, the integrin alpha v chain. This approximately 120kDa surface molecule non-covalently associates with the beta subunits of the integrin family including beta3 (CD61), beta1 (CD29), beta5 and beta6 to form receptors for extracellular matrix components. Heterodimers of CD51/CD61 are expressed by platelets, T cells and granulocytes and mediate adhesion to fibrinogen, fibronectin, vitronectin and thrombospondin.Applications Reported: The RMV-7 antibody has been reported for use in flow cytometric analysis, immunoprecipitation, and functional assays. Soluble RMV-7 blocks adhesion to fibronectin and vitronectin and immobilized RMV-7 induces activation. (Please use Functional Grade purified RMV-7, cat. 16-0512, in functional assays.).Applications Tested: The RMV-7 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD51 (Integrin alpha V)
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P43406
Vitronectin Receptor alpha chain, VNR
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry, Functional Assay, Immunoprecipitation, Neutralization
RMV-7
Unconjugated
Itgav
Liquid
Itgav
IgG1, kappa, kappa
500μg
4° C
Primary
16410
Videos

For Research Use Only.