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CD56 (NCAM) Mouse anti-Human, Non-human primate, Rhesus Monkey, APC, Clone: TULY56, eBioscience™

Mouse Monoclonal Antibody

1086.00 SEK - 2185.00 SEK

Specifications

Antigen CD56 (NCAM)
Clone TULY56
Target Species Human, Non-human primate, Rhesus Monkey
Conjugate APC
Isotype IgG1, kappa
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Product Code Brand Quantity Price Quantity & Availability  
15567946
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Affymetrix eBioscience
17-0566-41
25 Tests
1086.00 SEK
25 tests
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Estimated Shipment
03-02-2021
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15577946
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Affymetrix eBioscience
17-0566-42
100 Tests
2185.00 SEK
100 tests
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In stock, ready to ship: 9
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Description

Description

Description: This TULY56 monoclonal antibody reacts with human CD56, also known as Neural Cell Adhesion Molecule (NCAM). CD56 is a highly glycosylated transmembrane molecule expressed by neurons and plays a role in the homotypic adhesion of neural cells. In the hematopoietic system, CD56 is expressed on NK cells and a subset of T cells referred to as NKT cells. Staining with TULY56 does not block binding of CMSSB, suggesting that the two antibodies recognize different epitopes. Additionally, TULY56 performs better after fixation and permeabilization than CMSSB. The TULY56 monoclonal antibody crossreacts with Rhesus macaque. Applications Reported: This TULY56 antibody has been reported for use in flow cytometric analysis. Applications Tested: This TULY56 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

NCAM, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig)-like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins.
Specifications

Specifications

CD56 (NCAM)
Human, Non-human primate, Rhesus Monkey
IgG1, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
TULY56
APC
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
RUO
SDS

For Research Use Only.