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CD59 Antibody (MACIF/1193) - IHC-Prediluted, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-48467

3893.00 SEK valid until 2025-12-16
BÄSTA PRIS på kampanj! Använd kampanjkod: "24090" för att få ditt kampanjpris.

Produktkod. 18122429

  • 4600.00 SEK / 7ml

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Beskrivning

Beskrivning

CD59 Monoclonal specifically detects CD59 in Human, Baboon (Negative), Equine (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY
Specifikationer

Specifikationer

CD59
Monoclonal
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
CD59
Recombinant full-length human CD59 protein (Uniprot: P13987)
Protein L or PEG purified
RUO
Primary
Reacts with human CD59, a 20kDa glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. CD59 is widely distributed on cells in all tissues. It inhibits formation of MAC, thus protecting cells from complement-mediated lysis. The expression of CD59 on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment, that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobinuria (PNH). It is useful for study on GPI-anchored proteins, PNH and CD59 functions.
Store at 4C.
IgM κ
Immunohistochemistry (Paraffin)
MACIF/1193
Immunohistochemistry-Paraffin
16.3A5, 1F5, 1F5 antigen, 20 kDa homologous restriction factor, CD59 antigen, CD59 antigen, complement regulatory protein, CD59 glycoprotein, CD59 molecule, complement regulatory protein, EJ16, EJ30, EJ30, EL32 and G344), EL32, FLJ38134, FLJ92039, G344, HRF20, HRF-20, human leukocyte antigen MIC11, Ly-6-like protein, lymphocytic antigen CD59/MEM43, MACIF, MAC-inhibitory protein, MAC-IP, MEM43, MEM43 antigen, membrane attack complex (MAC) inhibition factor, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MGC2354, MIC11MSK21, MIN1, MIN2, MIN3, MIRL, p18-20, protectin, surface anitgen recognized by monoclonal 16.3A5, T cell-activating protein
Mouse
20 kDa
7 mL
Cell Biology, Cellular Markers, Immunology, Signal Transduction, Stem Cell Markers
966
Human, Baboon (Negative), Equine (Negative)
Purified
Produktförslag

Produktförslag

Filmer
SDS
Dokument

Dokument

Certifikat
Kampanjer

Kampanjer

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