missing translation for 'onlineSavingsMsg'
Learn More

CD61 (Integrin beta 3), clone: VI-PL2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0619-82

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15247037

  • 952.00 SEK / 100µg

Estimated Shipment date
from Supplier 24-01-2019
Add to basket



Description: The VI-PL2 monoclonal antibody reacts with human CD61, also known as integrin beta 3 and GPIIIa. CD61 is a 90-110kDa member of the beta integrin family expressed by a wide variety of cells, including leukocytes, platelets, endothelial and smooth muscle cells. CD61 binds non-covalently with the alpha integrins CD41 and CD51, to form the alpha IIb beta3 (CD41/CD61) and alpha v beta3 (CD51/CD61) complexes. These alpha beta heterodimers are capable of mediating a variety of cellular responses including adhesion, trafficking, proliferaton and differentiation. The CD41/CD61 integrin has been shown to be involved in platelet aggregation, and binds to fibrinogen, von Willebrand Factor (vWF) and fibronectin. The CD51/CD61 integrin binds to matrix proteins including vitronectin, fibronectin, vWF and fibrinogen, and has been shown to have a strong role in modulating the migration and survival of angiogenic endothelial cells.This VI-PL2 antibody has also been shown to crossreact with canine and several non-human primate species, including baboon, rhesus, and cynomologus monkey.Applications Reported: This VI-PL2 antibody has been reported for use in flow cytometric analysis, immunoprecipitation, immunohistochemical staining, and functional assays.Applications Tested: This VI-PL2 antibody has been tested by flow cytometric analysis of human peripheral blood platelets. This can be used at less than or equal to 0.125 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.


CD61 (Integrin beta 3)
PBS with 0.09% sodium azide; pH 7.2
BDPLT2, CD61, GP3A, GPIIIa, GT, integrin beta-3, platelet glycoprotein IIIa, platelet membrane glycoprotein IIIa, ITGB3
Affinity chromatography
Baboon, Canine, Cynomolgus Monkey, Human, Rhesus Monkey
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Western Blot
IgG1, kappa, kappa
Store at 2-8°C.
102117791, 3690, 403788, 717379

For Research Use Only.