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CD62E (E-selectin), PE, clone: P2H3, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-0627-42

Additional Details : Weight : 0.23750kg

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Product Code. 15516806

  • 1948.00 SEK / 100 tests


EU Stock 3
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Description

Description

Description: The P2H3 monoclonal antibody reacts with human CD62E, a 97-115kDa member of the selectin family. CD62E, also known as E-selectin or endothelial-leukocyte adhesion molecule-1 (ELAM-1) is an adhesion molecule expressed by endothelial cells upon stimulation with cytokines including TNFalpha and IL-1beta. Induced expression of CD62E during inflammatory conditions is thought to mediate leukocyte rolling including the initial interaction of neutrophils with endothelium.The P2H3 monoclonal antibody also inhibits cellular adhesion to cytokine-activated endothelial cells.Applications Reported: This P2H3 antibody has been reported for use in flow cytometric analysis.Applications Tested: This P2H3 antibody has been pre-titrated and tested by flow cytometric analysis of TNF alpha-actiavted Human Umbilical Vein Endothelial Cells (HUVEC). This can be used at 5 μL (0.5 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD62E (E-Selectin)
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P16581
RP1-117P20.2, CD62E, ELAM, ELAM1, ESEL, LECAM2
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
P2H3
PE
SELE
Conjugated
SELE
IgG1
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
6401
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