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CD62L (L-Selectin) Monoclonal Antibody (DREG-56 (DREG56)), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

1188.00 SEK - 3220.00 SEK

Specifications

Clone DREG-56 (DREG56)
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
Conjugate APC
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15577956
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Affymetrix eBioscience
17-0629-42
100 Tests
3220.00 SEK
100 tests
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15567956
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Affymetrix eBioscience
17-0629-41
25 Tests This item is currently unavailable or has been discontinued.
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Description

Description

Description: The DREG-56 monoclonal antibody reacts with human CD62L, a 76 kDa member of the selectin family. CD62L is expressed by neutrophils, monocytes, and subsets of T, B, and NK cells and binds a number of glycosylated, fucosylated, sulfated sialylated glycoproteins including CD34, glycam-1 and MAdCAM-1. These interactions mediate rolling of lymphocytes on activated endothelium at the sites of inflammation and homing of cells to the high endothelial venules (HEV) of peripheral lymphoid tissues. Applications Reported: The DREG-56 (DREG56) antibody has been reported for use in flow cytometric analysis. Applications Tested: The DREG-56 (DREG56) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.5μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

The human CD62L is a 74-95 kDa glycoprotein member of the selectin family of adhesion receptors. L-Selectin is comprised of an aminoterminal C-type lectin binding domain, an epidermal growth factor-like domain, two short consensus repeat (SCR) sequences homologous to those found in complement binding proteins, a short spacer region, a transmembrane region and a short cytoplasmic region. Human CD62L (L-Selectin) is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes and polymorphonuclear cells.
Specifications

Specifications

DREG-56 (DREG56)
Flow Cytometry
APC
Mouse
Human
6402
IgG1 κ
Affinity chromatography
Antibody
5 μL/Test
Monoclonal
Liquid
RUO
P14151
SELL
Primary
4° C, store in dark, DO NOT FREEZE!
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