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CD68 Mouse anti-Human, Clone: 815CU17, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0687-82

Additional Details : Weight : 0.09500kg

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Product Code. 15557426

  • 1966.00 SEK / 100µg


Estimated Shipment
11-01-2021
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Description

Description

Applications Tested: This 815CU17 antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded human tissue using low or high pH antigen retrieval and can be used at less than or equal to 5 μg/mL.The 815CU17 antibody has been tested by western blot analysis of reduced PBMC lysate and can be used at less than or equal to 5 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predomitly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human maligcies, including several Acute Myeloid Leukemia studies.
Specifications

Specifications

CD68
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P34810
CD68
IgG1, kappa
100 μg
4° C
Primary
968
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
815CU17
Unconjugated
CD68
Liquid
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
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