missing translation for 'onlineSavingsMsg'
Learn More

CD70 Rat anti-Mouse, PE, Clone: FR70, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-0701-82

Additional Details : Weight : 0.25000kg

 View more versions of this product

Product Code. 15218589

  • 1744.00 SEK / 100µg

In stock, ready to ship: 2

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Description: The FR70 monoclonal antibody reacts with mouse CD70, a 30-33 kDa type II transmembrane glycoprotein. CD70 is a member of the TNF family and is expressed by activated mouse T and B lymphocytes. Interaction of CD70 with CD27, its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation. Applications Reported: This FR70 antibody has been reported for use in flow cytometric analysis. Applications Tested: This FR70 antibody has been tested by flow cytometric analysis of LPS-stimulated mouse splenocytes. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Specifications

Specifications

CD70
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
O55237
CD27LG, Cd27l, Tnfsf7
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
FR70
PE
Cd70
Liquid
Cd70
IgG2b, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
21948
Videos
SDS
Documents
Certificates

For Research Use Only.