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CD70 Rat anti-Mouse, PE, Clone: FR70, eBioscience™

Rat Monoclonal Antibody

1102.00 SEK - 2406.00 SEK

Specifications

Antigen CD70
Clone FR70
Target Species Murine
Conjugate PE
Isotype IgG2b, kappa
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15208589
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Affymetrix eBioscience
12-0701-81
50 μg
1102.00 SEK
50µg
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Estimated Shipment: 12-08-2021
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15218589
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Affymetrix eBioscience
12-0701-82
100 μg
1744.00 SEK
100µg
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In stock, ready to ship: 2
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15228589
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Affymetrix eBioscience
12-0701-83
200μg This item is currently unavailable or has been discontinued.
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Description

Description

Description: The FR70 monoclonal antibody reacts with mouse CD70, a 30-33 kDa type II transmembrane glycoprotein. CD70 is a member of the TNF family and is expressed by activated mouse T and B lymphocytes. Interaction of CD70 with CD27, its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation. Applications Reported: This FR70 antibody has been reported for use in flow cytometric analysis. Applications Tested: This FR70 antibody has been tested by flow cytometric analysis of LPS-stimulated mouse splenocytes. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Specifications

Specifications

CD70
Murine
IgG2b, kappa
Monoclonal
Conjugated
Store at 2-8°C. Do not freeze. Light-sensitive material.
FR70
PE
Flow Cytometry
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
RUO
SDS
Product Certifications

For Research Use Only.