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CD71 (Transferrin Receptor) Mouse anti-Human, Clone: OKT9 (OKT-9), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0719-80

Additional Details : Weight : 0.01000kg

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Product Code. 15247067

  • 1034.00 SEK / 25µg


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Description

Description

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregcy, irritable bowel syndrome and in HIV patients.
Specifications

Specifications

CD71 (Transferrin Receptor)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P02786
CD71, T9, TFR, TFR1, TR, TRFR, p90, transferrin receptor protein 1
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OKT9 (OKT-9)
Unconjugated
TFRC
Liquid
TFRC
IgG1, kappa
25 μg
4° C
Primary
7037
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