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CD8a Mouse anti-Human, Alexa Fluor® 700, Clone: OKT8 (OKT-8), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 56-0086-41

Additional Details : Weight : 0.23750kg

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Product Code. 15580327

  • 944.00 SEK / 25 tests


Estimated Shipment
14-12-2020
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Description

Description

- test size: has been pre-titrated and tested by flow cytometric analysis of human peripheral blood leukocytes. This can be used at 5 μL (0.06 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Alexa Fluor™ 700 emits at 723 nm and can be excited with the red laser (633 nm). Most instruments will require a 685 LP mirror and 710/20 filter. Please make sure that your instrument is capable of detecting this fluorochrome. Excitation: 633-647 nm; Emission: 723 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered. CD8 (Cluster of Differentiation 8) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediate efficient cell-cell interactions within the immune system. The CD8 antigen acts as a co-receptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer (NK) cells, subpopulations of peripheral blood null cells, thymocytes and bone marrow cells. The CD8 co-receptor functions as either a homodimer composed of two alpha chains, or as a disulfide-linked heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. The majority of CD8+ T cells express CD8 as a alpha/beta heterodimer. In HIV, the HIV-2 envelope glycoprotein binds CD8 alpha chain (but not the beta chain).
Specifications

Specifications

CD8a
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P01732
CD8, Leu-2, MAL, p32, CD8a
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
OKT8 (OKT-8)
Alexa Fluor™ 700
CD8A
Liquid
CD8A
IgG2a, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
925
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SDS
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For Research Use Only.