missing translation for 'onlineSavingsMsg'
Learn More

CD85g (ILT7), PE, clone: eBio17G10.2 (17G10.2), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-5179-42

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15507006

  • 2450.00 SEK / 100 tests


EU Stock 1
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

Description: The eBio17G10.2 monoclonal antibody reacts with human immunoglobulin-like transcript 7 (ILT7), also known as CD85g. ILT7 is part of the leukocyte immunoglobulin-like receptor (LIR) gene family and associates with Fc epsilon R1 gamma to form a functional complex which transduces ITAM-mediated signals that negatively modulates TLR-induced type I IFN production by human plasmacytoid dendritic cells. ILT7 is expressed exclusively on plasmacytoid dendritic cells and is absent in monocyte derived DCs. Treatment with IL-3 or CpG causes a decrease in expression. Double staining of human PBMCs with eBio17G10.2 and anti-pDC marker BDCA2 yields virtually complete co-staining. Cross linking of ILT7 with eBio17G10.2 antibody causes reduced transcription of IFN alpha1, IFN alpha2, IFN alpha4 and IFN beta.Applications Reported: This eBio17G10.2 (17G10.2) antibody has been reported for use in flow cytometric analysis.Applications Tested: This eBio17G10.2 (17G10.2) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD85g (ILT7)
eBio17G10.2 (17G10.2)
PE
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
ILT-7, LILRA4
IgG1
RUO
Primary
Human
Videos