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CD85j (ILT2) Mouse anti-Human, eFluor 450, Clone: HP-F1, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 48-5129-42

Additional Details : Weight : 0.01000kg

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Product Code. 16606384

  • 5750.00 SEK / Pack of 100
Estimated Shipment: 23-08-2022
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Description

Description

The monoclonal antibody HP-F1 recognizes CD85j, also known as ILT2, LILRB1, and LIR1. CD85j is a member of the ILT/LIR/MIR family. CD85j is a single transmembrane glycoprotein with a long cytoplasmic domain containing 4 ITIMs which signal through interactions with SHP-1. Expression is found on myeloid cells (monocytes and dendritic cells) and some lymphoid cells including, subsets of NK, T and B cells. Expression has been correlated with leukemias such as ALL and CLL. Expression on CD8+ cells correlates with effector cell function and plays an important role in viral infections, including HIV, Ebstein Barr and CMV. The ligands for CD85j are MHC Class I molecules such as HLA-G, A, F, B27, E and F. The monoclonal antibody HP-F1 has been shown to reduce the amount of CD16- dependent cytolytic activity of functional NK cells. Applications Reported: This HP-F1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This HP-F1 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5uL (0.25ug) per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100uL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. eFluor 450 is an alternative to Pacific Blue. eFluor 450 emits at 446 nm and is excited with the violet laser line (405 nm).Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser

CD85j (ILT2) Monoclonal antibody specifically detects CD85j (ILT2) in Human samples. It is validated for Flow Cytometry
Specifications

Specifications

CD85j (ILT2)
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Q8NHL6
Mouse
100 Tests
Primary
Human
Antibody
IgG1 κ
Flow Cytometry
HP-F1
eFluor 450
LILRB1
CD85 antigen-like family member J; CD85j; Ig-like transcript 2; ILT2; ILT-2; Immunoglobulin-like transcript 2; leucocyte Ig-like receptor B1; leukocyte immunoglobulin like receptor B1; leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform; leukocyte immunoglobulin-like receptor subfamily B member 3-like; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1; LILRB1; LIR1; LIR-1; LOC100912456; MIR7; MIR-7; Monocyte/macrophage immunoglobulin-like receptor 7; myeloid inhibitory receptor 7; PIRB; PIR-B
Affinity Purified
RUO
10859
4° C, store in dark, DO NOT FREEZE!
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