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CD8a Mouse anti-Human, Alexa Fluor® 488, Clone: OKT8 (OKT-8), eBioscience™

Mouse Monoclonal Antibody

1282.00 SEK - 2140.00 SEK

Specifications

Antigen CD8a
Clone OKT8 (OKT-8)
Target Species Human
Conjugate Alexa Fluor® 488
Isotype IgG2a
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15500187 View Documents Affymetrix eBioscience
53-0086-41
25 Tests 1282.00 SEK
25 tests View alternative products
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Estimated Shipment date
from Supplier 23-08-2019
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15510187 View Documents Affymetrix eBioscience
53-0086-42
100 Tests 2140.00 SEK
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EU Stock 17
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Description

Description

CD8 (Cluster of Differentiation 8) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediate efficient cell-cell interactions within the immune system. The CD8 antigen acts as a co-receptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer (NK) cells, subpopulations of peripheral blood null cells, thymocytes and bone marrow cells. The CD8 co-receptor functions as either a homodimer composed of two alpha chains, or as a disulfide-linked heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. The majority of CD8+ T cells express CD8 as a alpha/beta heterodimer. In HIV, the HIV-2 envelope glycoprotein binds CD8 alpha chain (but not the beta chain).
Specifications

Specifications

CD8a
Human
IgG2a
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
OKT8 (OKT-8)
Alexa Fluor® 488
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.