missing translation for 'onlineSavingsMsg'
Learn More

CD8a Mouse anti-Human, Biotin, Clone: HIT8a, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-0089-82

Additional Details : Weight : 0.25000kg

Product Code. 15239439

  • 1532.00 SEK / 100µg


EU Stock 3
Add to basket

Description

Description

CD8 (Cluster of Differentiation 8) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediate efficient cell-cell interactions within the immune system. The CD8 antigen acts as a co-receptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer (NK) cells, subpopulations of peripheral blood null cells, thymocytes and bone marrow cells. The CD8 co-receptor functions as either a homodimer composed of two alpha chains, or as a disulfide-linked heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. The majority of CD8+ T cells express CD8 as a alpha/beta heterodimer. In HIV, the HIV-2 envelope glycoprotein binds CD8 alpha chain (but not the beta chain).
Specifications

Specifications

CD8a
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P01732
CD8, Leu-2, MAL, p32, CD8a
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
HIT8a
Biotin
CD8A
Liquid
CD8A
IgG1, kappa
100 μg
4° C, do not freeze
Primary
925
Videos

For Research Use Only.