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CD93 (AA4.1), Biotin, clone: AA4.1, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-5892-82

Additional Details : Weight : 0.25000kg

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Product Code. 15239909

  • 1376.00 SEK / 100µg


EU Stock 1
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Description

Description

Description: The AA4.1 monoclonal antibody reacts with mouse C1qRp, an approximately 130-140kDa C-type lectin-like type I transmembrane protein. The AA4.1 antigen was originally identified as an antigen expressed on early stages of B cell development in bone marrow. Adult spleen and fetal liver also have detectable numbers of AA4.1^+ cells. In combination with other markers of hematopoietic progenitor cells such as Thy-1, Sca-1, c-Kit, CD43, and CD24, the bone marrow Lymphoid-Committed Progenitors (CLP) can be segregated into more primitive and more differentiated subsets based on expression of AA4.1. Correlated expression of surface IgM (sIgM), CD23, and AA4.1 antigen has also been used to define three nonproliferative subpopulations of immature/transitional peripheral B cells designated: T1 (AA4.1^+/CD23^-/sIgMhi), T2 (AA4.1^+/CD23^+/sIgMhi), and T3 (AA4.1^+/CD23^+/sIgMlo). AA4.1 is also reported to be expressed in cytoplasmic vesicles in endothelial cells, megakaryoblasts, and platelets. It is reported that monoclonal antibodies AA4.1 and 493 recognize different epitopes of the same molecule.Applications Reported: The AA4.1 antibody has been reported for use in flow cytometric analysis.Applications Tested: The AA4.1 antibody has been tested by flow cytometric analysis of mouse bone marrow and splenocyte cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD93 (AA4.1)
Monoclonal
0.5mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
O89103
C1QR1, C1qR(P), C1qRP, CDw93, ECSM3, MXRA4, dJ737E23.1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry
AA4.1
Biotin
Cd93
Liquid
Cd93
IgG2b, kappa, kappa
100μg
Store at 2-8°C. Do not freeze.
Primary
17064
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