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CD98 Rat anti-Mouse, PE, Clone: RL388, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-0981-81

Additional Details : Weight : 0.25000kg

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Product Code. 15208629

  • 1006.00 SEK / 50µg

In stock, ready to ship: 1

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Description

Description

Description: The RL388 monoclonal antibody reacts with mouse CD98, also known as 4F2 antigen and Ly-10. RL388 detects a disulfide-linked heterodimer complex (130 kDa) composed of a glycosylated heavy (86 kDa) and a nonglycosylated light (39 kDa) subunits. CD98 is expressed on the surface of activated lymphocytes and is involved in cell activation and calcium flux events. Applications Reported: The RL388 antibody has been reported for use in flow cytometric analysis. Applications Tested: The RL388 antibody has been tested by flow cytometric analysis of activated and resting mouse splenocytes. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.
Specifications

Specifications

CD98
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P10852
4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
RL388
PE
Slc3a2
Liquid
Slc3a2
IgG2a, kappa
50 μg
4° C, store in dark, DO NOT FREEZE!
Primary
17254
Videos
SDS
Documents

For Research Use Only.