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CDC37 Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10218-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16826463

  • 3313.85 SEK / 150µL
Estimated Shipment: 08-12-2021

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Description

Description

In S. cerevisiae, Cdc37 has been shown to be an important regulator of cell division cycle through its action on cyclin-dependent kinases (CDK′s). Cdc37 has also been associated with signaling pathways and kinases unrelated to cell cycle control, including v-Src, casein kinase II, MPS1 kinase and the sevenless receptor tyrosine kinase. Interestingly, HSP90 has also been shown to be associated with many of the same cellular targets as Cdc37. It has now been shown that Cdc37 is the same protein previously described as p50 which has been found to be associated with many of the same proteins as HSP90. Among others, Cdc37/p50 has been found complexed with Src-family kinases (Fyn, Yes, Fes, Lck and Fgr), Raf and pp60v-src. More recently, Cdc37 has been shown to be a chaperone independently and in concert with HSP90. In fact, Cdc37 is necessary for the binding of HSP90 to Cdk4.
Specifications

Specifications

CDC37
0.2 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q16543, Q61081, Q63692
CDC37, CDC37A, Hsp90 co chaperone Cdc37, P50CDC37
Rabbit
IgG
150 μL
-20°C
Primary
11140, 114562, 12539
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Unconjugated
CDC37
Liquid
Cdc37
CDC37 Fusion Protein Ag0267
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Non-human Primate, Rat
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Special Offers

Special Offers