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Invitrogen™ CDK2/cyclin E1 Recombinant Human Protein

CDK2 is a member of the Cyclin-Dependent Kinase family that is ubiquitously expressed. Recombinant full-length human CDK2 and CyclinE1 were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag on both proteins.

3790.00 SEK - 57900.00 SEK

Specifications

Host Species Human
Protein Tag GST Tag
Recombinant Yes
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15438943
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Invitrogen™
PV6295
10μg
3790.00 SEK
10µg
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Estimated Shipment: 03-06-2022
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15448943
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Invitrogen™
PV6296
100μg
12940.00 SEK
100µg
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15458943
View Documents Promotion Details
Invitrogen™
PV6297
1mg
57900.00 SEK
1mg
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Estimated Shipment: 03-06-2022
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Description

Description

CDK2 is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. CDK2 associates with and is regulated by the regulatory subunits of the complex including Cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). CDK2 phosphorylates multiple cellular substrates including SMAD3 and FOXO1. Phosphorylation of FOXO1 leads to its inhibition.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Specifications

Specifications

Human
GST Tag
Yes
SDS
Product Certifications