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CF106 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA556949
Additional Details : Weight : 0.02000kg
Description
Immunogen sequence: MEGMDVDLDP ELMQKFSCLG TTDKDVLISE FQRLLGFQLN PAGCAFFLDM TNWNLQAAIG AYYDFESPNI SVPSMS Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.
Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF (PubMed:29802199). Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP (PubMed:29802199). [UniProt]Specifications
| CF106 | |
| Polyclonal | |
| Unconjugated | |
| C6orf106 | |
| AU020189; C030010A15; C6orf106; C80239; chromosome 6 open reading frame 106; D17Wsu92e; dJ391O22.4; DNA segment, Chr 17, Wayne State University 92, expressed; FP852; Ilrun; Inflammation and lipid regulator with UBA-like and NBR1-like domains protein; Protein ILRUN; uncharacterized protein C6orf106; uncharacterized protein C6orf106 homolog | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 64771 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry, Western Blot | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9H6K1 | |
| C6orf106 | |
| Recombinant protein corresponding to Human CF106 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Research Use Only