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  5. Tocris Bioscience™ CGS 15943

Tocris Bioscience™ CGS 15943
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Product Code. 18084132
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Kvantitet:
10 mg
50 mg
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Product Code. 18084132

Brand: Tocris Bioscience™ 1699/50

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Description

Potent adenosine receptor antagonist

CGS 15943 is a potent adenosine receptor antagonist (Ki values are 3.5, 4.2, 16 and 51 nM for human A1, A2A, A2B and A3 receptors respectively). Inhibits the catalytic subunit of the class IB PI3K isoform p110γ (IC50 = 1.1 μM). Blocks HCC and HDAC cell proliferation in vitro via inhibition of the PI3K/Akt pathway; reduces proliferation of ER+ breast cancer cells. Also acts as a BMP-4 mimetic to stimulate osteogenic differentiation. Orally active in vivo.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 104615-18-1
Molekylformel C13H8ClN5O

Specifications

Kemiskt namn eller material CGS 15943
Kvantitet 50 mg
Formel vikt 285.69
Renhet >99%
Molekylvikt (g/mol) 285.69
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