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CHEK2 (CHK2) Recombinant Human Protein

CHEK2 (CHK2) Recombinant Human Protein

Brand:  Invitrogen PR5460B

Additional Details : Weight : 0.01000kg

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Product Code. 15448453

  • 12870.00 SEK / 100µg


Estimated Shipment date
from Supplier 27-12-2017
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Disclaimers:

For Research Use Only. Not for use in diagnostic procedures.


Description

Description

CHEK2 (CHK2) is a serine⁄threonine kinase and a component of the DNA damage checkpoint pathway. A mutation in this gene has been linked to cancer. CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins.
Specifications

Specifications

NP_009125
Protein assays and analysis
Frozen
CHEK2 (CHK2) Recombinant Human Protein
100μg
For research use only. Not for use in diagnostic procedures
CHEK2 (CHK2)
CHEK2 (CHK2) was pre-diluted in enzyme dilution buffer and assayed in 12.5mM Tris (pH 7.5), 10mM MgCl2, 1mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL CHKtide substrate peptide (KKKVSRSGLYRSPSMPENLNRPR) and trace [32P]-γ-ATP for 10 minutes at 30°C
Baculovirus
CHEK2 (CHK2) Recombinant Human Protein
Human
0.32mg/mL
Frozen
66kDa
80% by SDS-PAGE
–80°C
1 Each
CHEK2 (CHK2) Recombinant Human Protein
Kinase assay
RAD53
3,000nmoles of phosphate transferred to CHKtide substrate peptide (KKKVSRSGLYRSPSMPENLNRPR) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 0.42μg/mL
His Tag
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