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Tocris Bioscience™ Chloroquine diphosphate

Beskrivning
Chloroquine diphosphate is an antimalarial drug. Inhibits cell growth and induces cell death in numerous cancer cell lines; inhibits cell proliferation and viability and induces apoptosis in 4T1 mouse breast cancer cells in vitro. Exhibits antimetastatic activity. Also inhibits autophagy via a mechanism distinct from that of 3-methyladenine (Cat. No. 3977). Blocks receptor-mediated endocytosis of mannose-glycoconjugates by macrophages. Inhibits SARS-CoV-2 infection in vitro (EC50 = 1.13 μM). Chloroquine improves efficacy of adeno-associated viral gene transduction in vivo and in vitro, as well as enhancing non-viral gene transfection in breast cancer cells. Tocris products are for biomedical research use only. They are not intended for human or veterinary use.
Specifikationer
Specifikationer
| Kemiskt namn eller material | Chloroquine diphosphate |
| CAS | 50-63-5 |
| Kvantitet | 50 mg |
| Molekylformel | C18H32ClN3O8P2 |
| Formel vikt | 515.86 |
| Renhet | >99% |
| Molekylvikt (g/mol) | 515.86 |
Produkttitel
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