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CHM Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA551870
Additional Details : Weight : 0.02000kg
Description
Immunogen sequence: SRKDKTIQHV EVFCYASQDL HEDVEEAGAL QKNHALVTSA NSTEAADSAF LPTEDESLST MSCEMLTEQT PSSDPENALE VNGAEVTGEK ENHCDDKTCV PSTSAEDMSE NVPIAEDTTE QPKKNRITYS QIIKEG Highest antigen sequence identity to the following orthologs: Mouse - 58%, Rat - 66%.
Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.Specifications
| CHM | |
| Polyclonal | |
| Unconjugated | |
| CHM | |
| CHM; CHM, Rab escort protein 1; choroideraemia protein homolog; choroideremia (Rab escort protein 1); Choroideremia protein; Choroideremia protein homolog; choroidermia; choroidermia (RAB escort protein 1); DXS540; GGTA; HSD-32; Rab escort protein 1; rab proteins geranylgeranyltransferase component A 1; REP1; REP-1; TCD; TCD protein | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 1121 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry | |
| 0.3 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| P24386 | |
| CHM | |
| Recombinant protein corresponding to Human CHM | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Research Use Only