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Clotrimazole
Beskrivning
Clotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Clotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1.
Solubility
Soluble in chloroform, DMSO, DMF and alcohols
Notes
Store at room temperature. Incompatible with oxidizing agents.
Specifikationer
Specifikationer
| Kemiskt namn eller material | Clotrimazole |
| Typ | Clotrimazole |
| Fysisk form | Powder |
| Smältpunkt | 141°C to 149°C |
| Färg | White |
| Kvantitet | 25 g |
| Merck Index | 14,2417 |
| Löslighetsinformation | Soluble in chloroform, DMSO, DMF and alcohols |
| Formel vikt | 344.84 |
RUO – Research Use Only
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