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Contactin 2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA552939
Additional Details : Weight : 0.02000kg
Description
Immunogen sequence: RHFVSQTTGN LYIARTNASD LGNYSCLATS HMDFSTKSVF SKFAQLNLAA EDTRLFAPSI KARFPAETYA LVGQQVTLEC FAFGNPVPRI KWRKVDGSLS PQWTTAEPTL QIPSVSFEDE GTYECEAENS KGRDTVQ Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.
Contactin 2 (CNTN2, transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunoglobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.Specifications
Contactin 2 | |
Polyclonal | |
Unconjugated | |
CNTN2 | |
Axonal glycoprotein TAG-1; axonin; Axonin 1; Axonin1; axonin-1; axonin-1 cell adhesion molecule; AXT; Cntn2; contactin 2; contactin 2 (axonal); contactin 2 (transiently expressed); Contactin2; contactin-2; D130012K04Rik; DKFZp781D102; FAME5; MGC157722; TAG1; TAG-1; TAG-564; Tax; TAX1; TAX-1; transient axonal glycoprotein 1; transiently-expressed axonal glycoprotein | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
6900 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry | |
0.05 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q02246 | |
CNTN2 | |
Recombinant protein corresponding to Human Contactin 2 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Research Use Only