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CRTC2/TORC2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 12497-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16840244

  • 3665.00 SEK / 150µL
Estimated Shipment: 07-12-2022
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Description

Description

CRTC2, also known as TORC2 (Transducers Of Regulated cAMP Response Element-Binding (CREB)) 2 and the related protein CRTC1 are potent CREB coactivators that are exported from the nucleus in a CRM1-dependent manner via phosphorylation-dependent interactions. Studies suggest that their phosphorylation and nuclear/cytoplasmic shuttling play an important role in the regulation of gluconeogenesis by cAMP. CRTC2 is present in both B and T-lymphocytes and abundantly expressed in the thymus. Its activity is important in regulating the expression of genes involved in cellular energy metabolism while CRTC1 is essential for energy balance and fertility.
Specifications

Specifications

CRTC2/TORC2
Polyclonal
Unconjugated
CRTC2
CRTC2, RP11 422P24.6, TORC 2, TORC2, Transducer of CREB protein 2
Rabbit
Antigen Affinity Chromatography
RUO
200186, 310615, 74343
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.45 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q3LRZ1, Q3U182, Q53ET0
Crtc2
CRTC2,TORC2 Fusion Protein Ag3167
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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