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Invitrogen™ CSNK1E (CK1 epsilon) R178C Recombinant Human Protein

This CSNK1E (CK1 epsilon) R178C Recombinant Human Protein (full length) was expressed in insect cells.

Brand:  Invitrogen™ A33498

Additional Details : Weight : 0.10000kg

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Product Code. 15960403

  • 4835.00 SEK / 10µg
Estimated Shipment: 06-03-2023
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Description

Description

  • This CSNK1E (CK1 epsilon) R178C recombinant human protein (full length) was expressed in insect cells
  • CSNK1E serine/threonine kinase is a member of the CK1 family which plays an important role in diverse cell processes, including DNA replication and repair
  • It is a regulator of Yes-associated protein (YAP) transcription coactivator, which is a key regulator of organ size and a candidate human oncogene
  • CSNK1E is activated by CCK2R and then phosphorylates PKD2 at Ser244
  • Phosphorylation of PKD2 leads to its nuclear accumulation, and efficient phosphorylation of nuclear PKD2 substrates in human gastric cancer cells
  • CSNK1E can phosphorylate topoisomerase (topo) II alpha at serine-1106 which regulates the enzyme activity and sensitivity to topo II-targeted drugs
  • CSNK1E (CK1 epsilon) R178C recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
  • Validated for use with the Z'-LYTE™ assay
  • Available in multiple pack sizes for convenient use
Specifications

Specifications

NP_001885.1
10 µg
Full Length
GST Tag
Dry Ice
Kinases & Inhibitors
Liquid
Human
73.6 kDa
CK1 Kinase Family
Yes
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol
Baculovirus
Full Length, Recombinant, Mutant
Kinase Assay
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