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Cyclopiazonic acid, 98%, Thermo Scientific™

Inhibitor of the sarco/endoplasmic reticulum calcium pump, calcium-ATPase

2695.00 SEK - 8865.00 SEK

Kemiska identifierare

CAS 18172-33-3
Molekylformel C20H20N2O3
Molekylvikt (g/mol) 336.391
MDL-nummer MFCD00167445
InChI-nyckel SZINUGQCTHLQAZ-AFAVFJNCSA-N
Synonym cyclopiazonic acid, alpha-cyclopiazonic acid, unii-x9tly4580z, ccris 4942, alpha-cyclopiazonate, cyclopyazonic acid, 6ar,10z,11as,11br-10-1-hydroxyethylidene-7,7-dimethyl-6a,7,11a,11b-tetrahydro-6h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indole-9,11 2h,10h-dione, 9h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-9-one, 2,6,6a,7,11a,11b-hexahydro-10-acetyl-7,7-dimethyl-11-hydroxy-, 6a-alpha,11a,11b-alpha, 6ar,11as,11br-10-acetyl-9-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-11h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-11-one, ambotzls-1020
PubChem CID 54711281
LEDER CC(=O)C1=C(C2C3C(CC4=C5C3=CNC5=CC=C4)C(N2C1=O)(C)C)O
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Product Code Brand Kvantitet Price Quantity & Availability  
15464169
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Thermo Scientific Alfa Aesar
J61594.MA
10mg
2695.00 SEK
10mg
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15474169
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Thermo Scientific Alfa Aesar
J61594.MF
50mg
8865.00 SEK
50mg
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Description

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
The use of Cyclopiazonic acid on Langendorff-perfused murine hearts displayed anti-arrhythmic effects. Also, administration of cyclopiazonic acid on rat soleus muscle showed a decrease in hormone sensitive lipase activity and triacylglycerol hydrolysis. It is also used as an inhibitor of endoplasmic reticulum Ca2+-ATPase.

Solubility
Soluble in DMSO (100 mM), ethanol (5 mM), DMF (∼20 mg/ml), and 1:1 DMSO:PBS(pH 7.2) (0.5 mg/ml). Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C Keep in a dry place. Keep away from strong oxidizing agents.
Specifications

Chemical Identifiers

18172-33-3
336.391
SZINUGQCTHLQAZ-AFAVFJNCSA-N
54711281
C20H20N2O3
MFCD00167445
cyclopiazonic acid, alpha-cyclopiazonic acid, unii-x9tly4580z, ccris 4942, alpha-cyclopiazonate, cyclopyazonic acid, 6ar,10z,11as,11br-10-1-hydroxyethylidene-7,7-dimethyl-6a,7,11a,11b-tetrahydro-6h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indole-9,11 2h,10h-dione, 9h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-9-one, 2,6,6a,7,11a,11b-hexahydro-10-acetyl-7,7-dimethyl-11-hydroxy-, 6a-alpha,11a,11b-alpha, 6ar,11as,11br-10-acetyl-9-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-11h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-11-one, ambotzls-1020
CC(=O)C1=C(C2C3C(CC4=C5C3=CNC5=CC=C4)C(N2C1=O)(C)C)O

Specifications

Cyclopiazonic acid
C20H20N2O3
UN2811
Soluble in DMSO (100 mM),ethanol (5 mM),DMF (∽20mg/ml),and 1:1 DMSO:PBS(pH 7.2) (0.5mg/ml). Insoluble in water.
CC(=O)C1=C(C2C3C(CC4=C5C3=CNC5=CC=C4)C(N2C1=O)(C)C)O
54711281
≥99%
18172-33-3
MFCD00167445
cyclopiazonic acid, alpha-cyclopiazonic acid, unii-x9tly4580z, ccris 4942, alpha-cyclopiazonate, cyclopyazonic acid, 6ar,10z,11as,11br-10-1-hydroxyethylidene-7,7-dimethyl-6a,7,11a,11b-tetrahydro-6h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indole-9,11 2h,10h-dione, 9h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-9-one, 2,6,6a,7,11a,11b-hexahydro-10-acetyl-7,7-dimethyl-11-hydroxy-, 6a-alpha,11a,11b-alpha, 6ar,11as,11br-10-acetyl-9-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-11h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-11-one, ambotzls-1020
SZINUGQCTHLQAZ-AFAVFJNCSA-N
336.391
336.39
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Safety and Handling

Safety and Handling

GHS H Statement
H300-H361
Fatal if swallowed.
Suspected of damaging fertility or the unborn child.

P264b-P270-P301+P310-P330-P501c

H300

missing translation for 'dotInformation' : Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.

missing translation for 'rtecsNumber' : UY8587000

missing translation for 'tsca' : No

Recommended Storage : Store at -20°C

SDS
Documents

Documents

Product Certifications

RUO – Research Use Only

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