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Invitrogen™ CYP17A1 Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA518504
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Beskrivning
This antibody is predicted to react with canine and feline based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
Specifikationer
| CYP17A1 | |
| Polyclonal | |
| Unconjugated | |
| CYP17A1 | |
| 17a-hydroxylase; 17-alpha-hydroxyprogesterone aldolase; CPT7; Cyp17; Cyp17a1; CYPXVII; cytochrome P450 17A1; cytochrome P450 family 17 subfamily A member 1; cytochrome p450 XVIIA1; cytochrome P450, 17; cytochrome P450, 17a1; cytochrome P450, family 17, subfamily A, polypeptide 1; cytochrome P450, subfamily 17; Cytochrome P450, subfamily XVII; cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia; Cytochrome P450c17; cytochrome P450-C17; HGNC:2593; P45017alpha; p450c17; P450-C17; S17AH; steroid 17-alpha hydroxylase; steroid 17-alpha-hydroxylase/17,20 lyase; Steroid 17-alpha-monooxygenase | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 1586 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| P05093 | |
| CYP17A1 | |
| Synthetic peptide sequence (LFKDGDQKLEK) corresponding to the internal amino acids of CYP17A1 (aa 134-145). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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