missing translation for 'onlineSavingsMsg'
Läs mer
  1. Home
  2. Products
  3. Proteinanalysreagenser
  4. Bioaktiva små molekyler
  5. STEMCELL Technologies D4476

STEMCELL Technologies D4476

Produktkod. 17100312
Encompass_Preferred
Change view
Klicka för att se tillgängliga alternativ
Kvantitet:
5 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Produktkod. Kvantitet
17100312 5 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Denna artikel kan inte returneras. Se returpolicy
Produktkod. 17100312 Leverantör STEMCELL Technologies Leverantörsnummer 74012

Please to purchase this item. Need a web account? Register with us today!

Denna artikel kan inte returneras. Se returpolicy

Beskrivning

Activin/NODAL/TGF-β pathway inhibitor; Inhibits CK1, ALK5 and p38 MAPK

  • D4476 is a selective, potent, and cell-permeant inhibitor of casein kinase (CK) 1 (Rena et al.) It inhibits CK1 and CK1δ from S
  • pombe (IC50 = 200 nM and 300 nM, respectively; Bain et al.; Rena et al.) It also inhibits transforming growth factor β1 (TGF-β1) type I receptor (ALK5) with IC50 = 500 nM (Rena et al.)
  • Along with forskolin (Catalog #72112) and 2-methyl-5-hydroxytryptamine, reprograms mouse somatic cells into pluripotent cells by acting as a chemical substitute for OCT4 (Hou et al.)
  • Reprograms mouse somatic cells into pluripotent cells by acting as a chemical substitute for OCT4 (Hou et al.)
  • Induces apoptosis of multiple myeloma cell lines (Hu et al.)
  • Exhibits anti-leukemic activity by selectively killing leukemia stem cells over normal hematopoietic stem and progenitor cells (Järås et al.)

Specifikationer

CAS 301836-43-1
Synonym Casein Kinase I Inhibitor
Kvantitet 5 mg
Molekylformel C23H18N4O3
Renhet ≥98%
Produkttitel
Välj ett problem

Genom att klicka på Skicka bekräftar du att du kan bli kontaktad av Fisher Scientific angående feedbacken du har lämnat i detta formulär. Vi kommer inte att dela din information för andra ändamål. All kontaktinformation som tillhandahålls ska också underhållas i enlighet med vår Sekretesspolicy.