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DDX5 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 26385-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16884865

  • 1355.00 SEK / 20µL
Estimated Shipment: 23-03-2023
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Description

Description

ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors and transforming agents, activate the ERK1 and ERK2 pathways. When growth factors bind to the receptor tyrosine kinase, Ras interacts with Raf, the serine/threonine protein kinase and activates it as well. Once actived, Raf phosphorylates serine residue in 2 further kinases, MEK1/2, which in turn phosphorylates tyrosine/threonine in extracellular-signal regulated kinase (ERK) 1/2. Upon activation, the ERKs either phosphorylate a number of cytoplasmic targets or migrate to the nucleus, where they phosphorylate and activate a number of transcription factors such as c-Fos and Elk-1.
Specifications

Specifications

DDX5
Polyclonal
Unconjugated
DDX5
DDX5, DEAD box protein 5, G17P1, HELR, HLR1, HUMP68, p68, RNA helicase p68
Rabbit
Antigen Affinity Chromatography
RUO
1655
-20°C
Liquid
Western Blot
0.35 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P17844
DDX5
DDX5 Fusion Protein Ag24821
20 μL
Primary
Human
Antibody
IgG
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