missing translation for 'onlineSavingsMsg'
Learn More

DLL4 (delta-like 4), Functional Grade, clone: HMD4-1, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-5948-82

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15248707

  • 1130.00 SEK / 100µg


Estimated Shipment date
from Supplier 29-05-2019
Add to basket

Description

Description

Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. Delta-like ligand 4 (DLL4), also know as Delta-4, is a homologue of the Drosophila delta protein, and functions as a transmembrane bound ligand to the notch receptor Notch1. DLL4 is expressed in the vasculature and plays a critical role in vascular development. It is induced by vascular endothelial growth factor (VEGF), as a negative feedback regulator to regulate angiogenic sprouting and promote the formulation of a differentiated vascular network. DLL4 has been found to be strongly expressed in tumor vessels of clear-cell renal tumors and bladder cancer, and inhibition of DLL4 results in increased vascular proliferation but defective maturation. This in turn leads to a decrease in tumor growth, with no apparent toxicity.
Specifications

Specifications

DLL4 (delta-like 4)
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
Q9JI71, D3ZHH1
MGC126344, hdelta2
Armenian Hamster
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse, Rat
Functional Assay
HMD4-1
Functional Grade
Dll4
Liquid
Dll4
IgG
100 μg
4° C
Primary
311332, 54485
Videos

For Research Use Only.