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Tocris Bioscience™ Dihydro-β-erythroidine hydrobromide
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Produktkod. 18063972
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18063972 10 mg
18094072 50 mg
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Produktkod. 18063972 Leverantör Tocris Bioscience™ Leverantörsnummer 2349/10

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Beskrivning

α4β2, muscle type and Torpedo nAChR antagonist

Dihydro-β-erythroidine hydrobromide is a member of the Erythrina alkaloids, it is a competitive nicotinic acetylcholine receptor antagonist with moderate selectivity for the neuronal α4 receptor subunit (IC50 values are 0.19 and 0.37 μM for α4β4 and α4β2 receptors, respectively). Antagonizes behavioral effects of nicotine in vivo. Dihydro-β-erythroidine blocks excitation of striatal GABAergic neurons, which completely suppress polysynaptic inhibition between striatal cholinergic interneurons. Dihydro-β-erythroidine hydrobromide has antidepressive-like effects in mice (forced swim and mouse suspension). Orally bioavailable
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Kemiska identifierare

CAS 29734-68-7
Molekylformel C16H22BrNO3

Specifikationer

Kemiskt namn eller material Dihydro-β-erythroidine hydrobromide
Kvantitet 10 mg
Formel vikt 356.26
Renhet >98%
Molekylvikt (g/mol) 356.26
Produkttitel
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