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DKK3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10365-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16876703

  • 3313.85 SEK / 150µL
Estimated Shipment: 02-12-2021

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Description

Description

DKK3, like DKK1, DKK2, and DKK4, possesses an N-terminal signal peptide and 2 conserved cysteine-rich domains, which are separated by a linker region and contain 10 cysteine residues each. The second cysteine region has a putative lipid-binding function that may facilitate WNT/DKK interactions at the plasma membrane. The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids. All DKKs have several potential sites for cleavage by furin-type proteases. Northern blot analysis revealed wide expression of the DKK3 transcript, with highest expression in heart, brain, and spinal cord. In situ hybridization reveals highest expression in mouse brain, eye, and heart.
Specifications

Specifications

DKK3
0.39 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9QUN9, Q9UBP4
Dickkopf 3, Dickkopf related protein 3, Dkk 3, DKK3, hDkk 3, REIC, RIG
Rabbit
IgG
150 μL
-20°C
Primary
27122, 50781
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
DKK3
Liquid
Dkk3
DKK3 Fusion Protein Ag0417
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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