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Tocris Bioscience™ DMH2

Type I BMP receptor inhibitor

Brand:  Tocris Bioscience™ 5580/50

Additional Details : CAS Number : 1206711-14-9 Weight : 0.00970kg

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Product Code. 18770128

  • 11369.03 SEK / 50mg
Estimated Shipment: 31-07-2024
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Description

Description

DMH2 is a type I BMP receptor inhibitor (Ki values are <1, 5.4 and 43 nM for ALK6, ALK3 and ALK2, respectively). Exhibits >30-fold selectivity over ALK4, ALK5, BMPR2, AMPK and VEGFR2. Also binds to TGFBR2 (Ki = 85 nM). Decreases growth and induces cell death of H1299 non-small cell lung carcinoma cells in vitro. Enhances liver regeneration in vivo.
Specifications

Specifications

4-[6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
50 mg
C27H25N5O2
>98%
1206711-14-9
BMP and Other Activin Receptor Inhibitors
451.52
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