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Tocris Bioscience™ DMH2
Type I BMP receptor inhibitor
2913.53 SEK - 11369.03 SEK
Specifications
| Chemical Name or Material | 4-[6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline |
|---|---|
| CAS | 1206711-14-9 |
| Target | BMP and Other Activin Receptor Inhibitors |
| Molecular Formula | C27H25N5O2 |
| Formula Weight | 451.52 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18770128
|
Tocris Bioscience™
5580/50 |
50 mg |
11369.03 SEK
50mg |
Estimated Shipment: 05-08-2024 Log in to see stock. |
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|
18716158
|
Tocris Bioscience™
5580/10 |
10 mg |
2913.53 SEK
10mg |
Estimated Shipment: 05-08-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Type I BMP receptor inhibitor (Ki values are <1, 5.4 and 43 nM for ALK6, ALK3 and ALK2, respectively). Exhibits >30-fold selectivity over ALK4, ALK5, BMPR2, AMPK and VEGFR2. Also binds to TGFBR2 (Ki = 85 nM). Decreases growth and induces cell death of H1299 non-small cell lung carcinoma cells in vitro. Enhances liver regeneration in vivo.Specifications
| 4-[6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | |
| BMP and Other Activin Receptor Inhibitors | |
| 451.52 |
| 1206711-14-9 | |
| C27H25N5O2 | |
| >98% |